This article looks at the experiences of the Social Enterprise Development Foundation of West Africa (SEND Foundation) in building the capacity of civil society groups and local government officials in resource-poor northern Ghana. The article uses these experiences as a case study to explore how the Ghana Poverty Reduction Strategy (GPRS) engages pro-poor and grassroots civil society organisations in facilitating participatory economic development in their local communities. The article has a two-fold focus on capacity building: increasing knowledge and understanding of the GPRS with civil society, and developing participatory monitoring and evaluation skills. The focus is on the Ghana HIPC Watch, which is a pilot project that aims to be a mechanism through which civil society organisations can engage in policy monitoring and evaluation. The central concerns of equity and accountability, particularly in terms of gender, emerged as important issues.